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COVID-19 Updates: Get the latest public information related to coronavirus disease 2019 (COVID-19) at

The Public Health Department is actively responding to COVID-19. At the same time, we continue to provide essential services in the safest way possible, including telephone or remote appointments (through your mobile phone or computer) and in-person visits when needed. 

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Vaccines & Immunizations

Who can use this service?

The Public Health Department offers general vaccines, travel shots or shots your child needs for school.

For children, shots are only available for MediCal-eligible or uninsured children.  If you are unsure about whether you qualify, please call (805) 781-5500.  Those with private insurance should see their pediatrician or pharmacist.

What is the process?

Step 1: Determine which vaccinations you need

The Public Health Department offers a range of vaccines. To determine the ones you need, check out the CDC's recommended vaccine schedule.  You can also check out the CDC recommendations for your age group, health status, pregnancy, and foreign travel.

Step 2: Call for an Appointment

Contact our office at (805) 781-5500 to schedule an appointment.  Let them know which vaccines you'll need.

Is there a charge for this service?

You may be eligible for no-cost services with Medi-Cal, CenCal, Medicare, or the Merck Vaccine Patient Assistance Program

Payment is due at time of visit. We accept cash, check, debit/credit cards (except American Express), Medicare, Medi-Cal, and Blue Shield PPO.

Many travel vaccines are not covered by insurance. 

See the fee list below. Please note that the total cost for your visit is the vaccine fee plus the office visit fee, and that some vaccinations require multiple doses. Fees are subject to change as our cost for vaccine can change at any time. 

Total cost = vaccine fee plus the office visit fee



Office Visit (1 vaccine)

$     30.00


Office Visit (2+ vaccines)

$     50.00



$   270.00


Hepatitis A

$     51.00


Hepatitis B

$     56.00


Hepatitis B (HEPLISAV-B)

$   152.00


Hepatitis A & B (Twinrix)

$     91.00



$     17.00


Human Papillomavirus (HPV)

$   260.00


Immune Globulin

$     22.00


Influenza (Flu) shot

$     10.00


Influenza (Flu) High Dose (65+ yrs)

$     56.00


Meningococcal (Bexero) (2-55 yrs)

$   180.00


Meningococcal (Menomune) (2+ yrs)

$   137.00


Meningococcal (Trumemba) (10-25 yrs)

$   168.00


Meningococcal (Menactra) (2-55 yrs)

$   137.00



$     90.00


Pneumococal (PPSV23) Pneumovax. (2+ yrs)

$   113.00


Pneumococal (PCV13) Prevnar (13+ yrs)

$   208.00


Polio Inactivated

$     38.00


Tdap (Boostrix) (10-18 yrs)

$     43.00


TB Screening

$     20.00


TB Skin Test

$     25.00


Typhoid Injection

$   119.00


Typhoid Oral

$     65.00


Varicella (chicken pox)

$   156.00


Yellow Fever  *see note on vaccine shortage below

$   172.00


Yellow Fever replacement card

$     5


Zostavax (60+ yrs)

$   273.00


* Yellow fever vaccine shortage: Due to a recent vaccine shortage, the Public Health Department does not currently have the yellow fever vaccine available. Stamaril, a yellow fever vaccine alternative, is currently available at Passport Health in Pismo Beach and the clinics listed here.

When and where is this service offered?

Vaccinations are provided by appointment only, Mon-Fri: 8:00 a.m. to 5:00 p.m. (excluding County Holidays) at the clinic locations below.  The Grover Beach location is closed on Fridays.

Location, directions and hours of operation

Click on location name to show hours of operation, directions and phone information

Public Health Department SLO Clinic

Monday - Friday 8-5

2191 Johnson Avenue San Luis Obispo, CA 93401

Tel: (805) 781-5500

Grover Beach Office

Monday - Thursday 8-5 (closed on Fridays).

286 South 16th Street Grover Beach, CA 93433

Tel: (805) 473-7050

Fax: (805) 474-7473

Paso Robles Office

Monday - Friday 8-5

723 Walnut Drive Paso Robles, CA 93446

Tel: (805) 237-3050

Fax: (805) 237-3057

Frequently Asked Questions

How often and for what should I be vaccinated?

The CDC provides easy-to-read vaccination schedules for children, teens and adults.

What vaccines do I need for my upcoming travel?

Depending on where you are traveling, you'll likely need to get some travel-related vaccines. Find the latest information from CDC based on your destination and make an appointment to get your travel shots 4-6 weeks before your trip so that you have enough time to build up immunity and get the best protection.

What vaccines should I get during pregnancy?

The CDC recommends you get the Tdap vaccine during each pregnancy (between 27 and 36 weeks of pregnancy) to help protect yourself and your baby. This will protect your baby after birth (and before they are old enough to get the vaccine themselves) from life-threatening whooping cough. The flu shot is also recommended if you are pregnant during flu season (October through May).

How do I get immunization records?

Call us at (805) 781-5500 to request a record of any immunizations you received at the San Luis Obispo County Public Health Department.  For vaccines received outside the Department, see tips for finding vaccine records.

For records of immunizations given in California from the late 1990’s to the present, consider checking the California Immunization Record (CAIR). While participation is still voluntary, your doctor may have reported your immunization to CAIR. Check with your provider or the Public Health Department if you have any questions.

If you try the above and still can't find your records, you will likely need to repeat some vaccines. Although this is time-consuming and inconvenient, it is not harmful to receive additional vaccine doses. For a few vaccines, blood tests can help determine if you’re already immune to certain diseases. Your healthcare provider can help you determine exactly what’s best for you.

Are vaccines safe?

The safety of vaccines is often a topic of media stories and blog postings. This attention may make you wonder, "How do we know our vaccines are safe?" In the United States, a number of safeguards are required by law to help ensure that the vaccines we receive are safe. Here are some important things to know about vaccine safety in the United States:

  • The safety of vaccines is thoroughly studied before they are licensed for public use.
  • There is a strong system in place to help scientists monitor the safety of vaccines.
  • Like any medicine, vaccines can cause side effects. However, serious adverse events from vaccines are rare.
  • Receiving combination vaccines or several different vaccines during one visit is very safe and offers the quickest protection again multiple diseases.

The CDC’s Vaccine Safety website answers common questions about vaccine safety.

What are the required school immunizations?

California Law requires that children entering public or private school, including childcare, preschool, elementary, or secondary schools, receive required immunizations. Visit for information about the law and the immunization requirements.

How do I know if the other children at my child’s school or child care are vaccinated?

Child care facilities and schools with low vaccination rates are at increased risk for outbreaks of vaccine-preventable diseases. Some children are allowed by California law to skip immunizations if a parent submits a medical exemption (PME) at enrollment. Other children may be admitted to child care on the condition they complete remaining vaccinations when due. To lookup vaccination rates at your child care or school, select one of the following: Child Care/Preschool | Kindergarten | 7th Grade

What if my child doesn’t feel well after the shot?

Sometimes children have mild reactions from vaccines, such as pain where the shot was given, a rash, or a fever. These reactions are normal and will usually go away soon. Once you and your child get home after your vaccination appointment, you can use a cool, wet cloth to ease redness, soreness, and swelling in the place where the shot was given. Reduce any fevers with a cool sponge bath. If your doctor approves, give non-aspirin pain reliever. You also can read your child stories, cuddle and praise your child, and show some extra attention. Find more information on what to if your child has discomfort after the shot. Contact your doctor if anything concerns you.

What is the difference between vaccines, vaccinations, and immunizations?

A vaccine is a product that produces immunity from a disease and can be administered through needle injections, by mouth, or through aerosol inhaled by the nose.

A vaccination is the injection of a killed or weakened organism that produces immunity in the body against that organism.

An immunization is the process by which a person becomes protected from a disease. Vaccines cause immunization, and there are also some diseases that cause immunization after an individual recovers from the disease.

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