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COVID-19 Updates: Get the latest public information related to coronavirus disease 2019 (COVID-19) at

The Public Health Department is actively responding to COVID-19. At the same time, the department continues to provide essential services in the safest way possible, including telephone or remote appointments (through your mobile phone or computer) and in-person visits when needed. For updates on COVID-19 in SLO County, visit For updates on other Public Health services, visit or call 805-781-5500.

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County Seal

Health Agency | Public Health

County of San Luis Obispo

Laboratory Phone Numbers

Regular Hours: Monday through Friday 8:00am - 5:00pm

  • Front Office (805) 781-5507
  • Supplies ordering (805) 781-5507
  • Laboratory (805) 781-5510
  • Supervisor (805) 781-5509
  • Director (805) 781-5512

Weekend Hours: 8:00 am - 6:30 pm

  • Microbiologist on call (805) 305-8188
  • After Hours EMERGENCY ONLY Laboratory Director (805) 459-9915